威尼斯官方入口—welcome(China)NO.1

王琦

博士 副教授,四川省“千人计划”特聘专家

王琦,威尼斯官方入口—welcome医学检验系副教授,硕士生导师,斯坦福大学访问学者,复旦大学博士。从事近红外一区、二区生物荧光探针及多肽药物研究。到目前为止,在Chemical Society Reviews, Analytical Chemistry, Theranostics, Chemical Communications, Journal of Materials Chemistry B等杂志上共发表论文二十余篇,申请国家专利6项,授权两项,转化一项。担受邀任Analytical Chemistry, Chemical Science, Chemical Communications等期刊审稿人。近年来主持及参与国家自然科学基金各一项,参与国家科技部重大研究计划973项目一项,国家级及省级大学生创新计划两项并获国家留学基金委资助于美国斯坦福大学研修。



研究方向:

1、多肽药物方向:基于化学固相合成法合成具有新型结构及功能的抗菌、抗肿瘤多肽,利用超分子自组装实现多肽药物的性能改进。

2、生物探针方向:开发及利用近红外荧光染料(NIR I, NIRII)结合多肽分子构建可用于生物小分子,金属离子,蛋白质检测的荧光探针。



代表论文:

1. X Zhu, R Zou, Q Wang*, J Wu*, A supramolecular peptide polymer from hydrogen-bond and coordination-driven self-assembly, Polymer Chemistry, 2018, 9, 69-76.

2. J Wu*, Q Meng, H Ren, H Wang, and J Wu, Q Wang*, Recent advances in peptide nucleic acid for cancer bionanotechnology, Acta Pharmacologica Sinica, 2017, 38, 798-805.

3. Y Liu, Q Wang, P She, J Gong, W Wu, S Xu, J Li, K Zhao, A Deng, Chitosan-coated hemoglobin microcapsules for use in an electrochemical sensor and as a carrier for oxygen, Microchimica Acta, 2016, 183 (11), 2847-2854.

4. Y Liu, J Gong, W Wu, Y Fang, Q Wang, H Gu, A novel bio-nanocomposite based on hemoglobin and carboxyl graphene for enhancing the ability of carrying oxygen, Sensors and Actuators B: Chemical, 2016, 222, 588-597.

5. R Zou,# Q Wang,# J Wu, J Wu, C Schmuck and H Tian, Peptide self-assembly triggered by metal ions, Chemical Society Reviews, 2015, 44, 5200-5219. (#Co-first author)

6. J Wu, R Zou, Q Wang, Y Xue, P Wei, S Yang, J Wu* & He Tian*, A peptide probe for the detection of neurokinin-1 receptor by disaggregation enhanced fluorescence and magnetic resonance signals, Scientific Reports, 2014, 4, 6487.

7. Q Wang,# X Shi,# X Zhu, M Ehlers, J Wu*, C Schmuck*, A fluorescent light-up probe as an inhibitor of intracellular β-tryptase, Chemical Communications, 2014, 50, 6120-6122. (#Co-first author)

8. Q Wang, L Chen, Y Long, H Tian, J Wu*, Molecular Beacons of Xeno-Nucleic Acid for Detecting Nucleic Acid, Theranostics, 2013, 3 (6), 395-408 (Cover figure).

9. X Zhu*, Q Wang, X Shi, F Liu, L Wang, H Wang, Development and analytical validation of an Enzyme-Linked Immunosorbent Assay (ELISA) for the detection of copper in human hair and serum samples, Analytical Methods, 2013, 5 (10), 2578-2583.

10. Q Wang, C Li, Y Zou, H Wang, T Yi*, C Huang, A highly selective fluorescence sensor for Tin (Sn4+) and its application in imaging live cells, Organic & Biomolecular Chemistry, 2012, 10 (33), 6740-6746.

11. X Yu, Q Liu, J Wu, M Zhang, X Cao, S Zhang, Q Wang, L Chen, T Yi*, Sonication-Triggered Instantaneous Gel-to-Gel Transformation, Chemistry-a European Journal, 2010, 16 (30), 9099-9106.

12. Q Wang, J Wu, Z Gong, Y Zou, T Yi*, C Huang, From vesicles to solid spheres: terminal functional group induced morphology modification, Soft Matter, 2010, 6 (12), 2679-2684.

13. 来晓芳;王吉德;徐新良;郭景玉;王琦, 绿色水处理剂聚天冬氨酸及其改性研究进展,现代化工,201333(4)pp 24-27+29

14. 易涛;邹莹;曹新华;王琦;夏倩,响应型分子功能材料及其在探针方面的应用,中国化学会第28届学术年会第8分会场摘要集,2012



专利:

1. 易涛、邹莹、肖述章、吴君臣、曹新华、王琦,一种含二芳乙烯基团的两亲性化合物及其制备方法和应用,中国,申请号:200910137059.4

2. 吴君臣,刘奔,邹荣峰,王琦,田禾,利那洛肽的制备方法,中国,申请号:201310556661.8

3. 王琦 朱晓霞 刘杨 弓瑾 吴伟平 鞠少卿 顾海鹰,一种基于纳米粒子-血红蛋白的人造血红细胞的制备方法,中国,申请号:201710172238.6

4. 王琦,弓瑾,吴铭敏,朱晓霞,顾心亮,张颖,一种近红外二区方酸喹啉染料及其制备方法,中国,申请号:201910242205.3






Baidu
sogou
XML 地图 | Sitemap 地图